(Revised after I noticed a purple colour cast).
It's an interesting time in image processing technology. There are genuine improvements in easy to use (read: hands free, almost) digital noise reduction features of consumer, off the shelf, software. I purchased Topaz Labs Denoise AI, like it a lot, use it a lot, for my photos.There are two algorithms - the standard and the Low Noise option. There are adjustment sliders for them. I've an affiliate link here if you want to buy it and also reward me.
DxO has just released version 4 of their PhotoLab - this has been a well known, well regarded general purpose raw processing program - the Elite Edition has an enhanced noise reduction feature named Prime Noise Reduction. Now there's Deep Prime.
I'm just testing at the moment. Below are crops of .tiff files from an Olympus E-PM2 raw file, shot at, ahem, ISO 25,000 - yes rubbish ISO, pretty much only useful for a snapshot rather than a polished professional photo. The full .TIFF files are downloadable via links.
When I first made the Topaz Denoise AI images, I ran Topaz Denoise as standalone, loading the Olympus .ORF raw file directly, then saved as .TIFF - for some reason there's a purple cast in the images, I didn't see any Colorspace option. Then I ran Topaz Denoise as an Adobe Photoshop plugin, loading the raw first through Adobe Camera Raw. This time there was no colour cast.
Hope this is useful.
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Olympus Workspace - Standard Noise Filter - .tiff file
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Topaz Denoise AI (Low Light Mode) directly loading the raw .orf file - .tiff file
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Topaz Denoise AI directly loading the raw .orf file - .tiff file
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Topaz Denoise AI through ACR / Photoshop - tiff file
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Topaz Denoise (Low Light mode) through ACR / Photoshop - tiff file
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Topaz Denoise (AI Clear mode) through ACR / Photoshop - tiff file
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